Version 5.4
Homo sapiens Protein: CLCN7
Summary
InnateDB Protein IDBP-745076.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CLCN7
Protein Name
Synonyms CLC-7; CLC7; OPTA2; OPTB4; PPP1R63;
Species Homo sapiens
Ensembl Protein ENSP00000461009
InnateDB Gene IDBG-8979 (CLCN7)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005216 ion channel activity
GO:0005247 voltage-gated chloride channel activity
Biological Process
GO:0006821 chloride transport
GO:0034220 ion transmembrane transport
GO:0044070 regulation of anion transport
GO:0055085 transmembrane transport
Cellular Component
GO:0016020 membrane
Protein Structure and Domains
PDB ID
InterPro IPR001807 Chloride channel, voltage gated
IPR002249 Chloride channel ClC-7
IPR014743 Chloride channel, core
PFAM PF00654
PRINTS PR00762
PR01118
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL I3L470
UniProt Splice Variant
Entrez Gene 1186
UniGene Hs.459649
RefSeq
HUGO HGNC:2025
OMIM 602727
CCDS
HPRD 04103
IMGT
EMBL AL031600 AL031705
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca