InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: NAA35

Summary

InnateDB Protein

IDBP-74522.5

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

NAA35

Protein Name

N(alpha)-acetyltransferase 35, NatC auxiliary subunit

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000354972

InnateDB Gene

IDBG-74520 (NAA35)

Protein Structure

UniProt Annotation

Function

Auxillary component of the N-terminal acetyltransferase C (NatC) complex which catalyzes acetylation of N-terminal methionine residues. Involved in regulation of apoptosis and proliferation of smooth muscle cells. {ECO:0000269PubMed:19398576}.

Subcellular Localization

Cytoplasm {ECO:0000269PubMed:19398576}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.

Experimentally validated
Total	5 [view]
Protein-Protein	5 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding

Biological Process

GO:0043066	negative regulation of apoptotic process
GO:0048659	smooth muscle cell proliferation

Cellular Component

GO:0005737	cytoplasm
GO:0005844	polysome
GO:0031417	NatC complex

Protein Structure and Domains

PDB ID

InterPro

IPR007244 NatC N(alpha)-terminal acetyltransferase, Mak10 subunit

PFAM

PF04112

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q5VZE5

PhosphoSite

PhosphoSite-Q5VZE5

TrEMBL

UniProt Splice Variant

Entrez Gene

60560

UniGene

Hs.436098

RefSeq

NP_078911

HUGO

HGNC:24340

OMIM

CCDS

CCDS6673

HPRD

11291

IMGT

EMBL

AK025266 AK026296 AL161447 AL161453 AL353743 BC117427 BC117429 CH471089

GenPept

AAI17428 AAI17430 BAB15097 BAB15435 CAH73155 CAI12659 CAI16313 EAW62702