Version 5.4
Homo sapiens Protein: GORASP2
Summary
InnateDB Protein IDBP-74806.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol GORASP2
Protein Name golgi reassembly stacking protein 2, 55kDa
Synonyms GOLPH6; GRASP55; GRS2; p59;
Species Homo sapiens
Ensembl Protein ENSP00000234160
InnateDB Gene IDBG-74804 (GORASP2)
Protein Structure
UniProt Annotation
Function Plays a role in the assembly and membrane stacking of the Golgi cisternae, and in the process by which Golgi stacks reform after mitotic breakdown. May regulate the intracellular transport and presentation of a defined set of transmembrane proteins, such as transmembrane TGFA. {ECO:0000269PubMed:10487747, ECO:0000269PubMed:21515684}.
Subcellular Localization Golgi apparatus membrane; Lipid-anchor. Membrane; Peripheral membrane protein.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 59 experimentally validated interaction(s) in this database.
Experimentally validated
Total 59 [view]
Protein-Protein 59 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0000278 mitotic cell cycle
GO:0006996 organelle organization
Cellular Component
GO:0000139 Golgi membrane
GO:0005794 Golgi apparatus
GO:0005886 plasma membrane
GO:0016020 membrane
Protein Structure and Domains
PDB ID
InterPro IPR001478 PDZ domain
IPR024958 GRASP55/65 PDZ-like domain
PFAM PF00595
PF13180
PF04495
PRINTS
PIRSF
SMART SM00228
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9H8Y8
PhosphoSite PhosphoSite-Q9H8Y8
TrEMBL B4DQF1
UniProt Splice Variant
Entrez Gene 26003
UniGene Hs.431317
RefSeq NP_056345
HUGO HGNC:17500
OMIM 608693
CCDS CCDS33325
HPRD 08303
IMGT
EMBL AC010092 AK023082 AK023201 AK027349 AK296698 AK298771 AL117430 BC007770 CH471058
GenPept AAH07770 AAY15076 BAB14395 BAB14459 BAB55054 BAG59292 BAG60913 CAB55919 EAX11227

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca