Version 5.4
| Homo sapiens Protein: GPR139 | |||||||||
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| Summary | |||||||||
| InnateDB Protein | IDBP-749078.3 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | GPR139 | ||||||||
| Protein Name | |||||||||
| Synonyms | |||||||||
| Species | Homo sapiens | ||||||||
| Ensembl Protein | ENSP00000458791 | ||||||||
| InnateDB Gene | IDBG-18134 (GPR139) | ||||||||
| Protein Structure |
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| UniProt Annotation | |||||||||
| Function | Orphan receptor. Seems to act through a G(q/11)-mediated pathway. | ||||||||
| Subcellular Localization | Cell membrane; Multi-pass membrane protein. | ||||||||
| Disease Associations | |||||||||
| Tissue Specificity | Expressed almost exclusively in the brain. Detected at very low levels in the peripheral tissues. {ECO:0000269PubMed:15845401}. | ||||||||
| Comments | |||||||||
| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Protein Structure and Domains | |||||||||
| PDB ID | |||||||||
| InterPro |
IPR000276
G protein-coupled receptor, rhodopsin-like IPR017452 GPCR, rhodopsin-like, 7TM IPR019427 7TM GPCR, serpentine receptor class w (Srw) |
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| PFAM |
PF00001
PF10324 |
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| PRINTS |
PR00237
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| PIRSF | |||||||||
| SMART | |||||||||
| TIGRFAMs | |||||||||
| Post-translational Modifications | |||||||||
| Modification | |||||||||
| Cross-References | |||||||||
| SwissProt | Q6DWJ6 | ||||||||
| PhosphoSite | PhosphoSite-Q6DWJ6 | ||||||||
| TrEMBL | |||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 124274 | ||||||||
| UniGene | Hs.446875 | ||||||||
| RefSeq | NP_001002911 | ||||||||
| HUGO | HGNC:19995 | ||||||||
| OMIM | |||||||||
| CCDS | CCDS32398 | ||||||||
| HPRD | 17062 | ||||||||
| IMGT | |||||||||
| EMBL | AB083594 AB196529 AK291384 AY255545 AY635179 BC137237 BC137238 CH471186 | ||||||||
| GenPept | AAI37238 AAI37239 AAO85057 AAT65818 BAB89307 BAD97440 BAF84073 EAW50306 | ||||||||