InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: EIF3C

Summary

InnateDB Protein

IDBP-749955.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

EIF3C

Protein Name

Synonyms

eIF3-p110; EIF3CL; EIF3S8;

Species

Homo sapiens

Ensembl Protein

ENSP00000456416

InnateDB Gene

IDBG-23122 (EIF3C)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 124 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Experimentally validated
Total	124 [view]
Protein-Protein	122 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	1 [view]
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003743	translation initiation factor activity
GO:0005488	binding
GO:0005515	protein binding
GO:0031369	translation initiation factor binding

Biological Process

GO:0001731	formation of translation preinitiation complex
GO:0006413	translational initiation
GO:0006446	regulation of translational initiation

Cellular Component

GO:0005852	eukaryotic translation initiation factor 3 complex
GO:0016282	eukaryotic 43S preinitiation complex
GO:0033290	eukaryotic 48S preinitiation complex

Protein Structure and Domains

PDB ID

InterPro

IPR000717 Proteasome component (PCI) domain
IPR008905 Eukaryotic translation initiation factor 3 subunit C, N-terminal domain
IPR016024 Armadillo-type fold

PFAM

PF01399
PF05470

PRINTS

PIRSF

SMART

SM00088

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite