InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: ATXN2L

Summary

InnateDB Protein

IDBP-750626.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

ATXN2L

Protein Name

Synonyms

A2D; A2LG; A2LP; A2RP;

Species

Homo sapiens

Ensembl Protein

ENSP00000454757

InnateDB Gene

IDBG-23203 (ATXN2L)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Membrane {ECO:0000269PubMed:11784712}; Peripheral membrane protein {ECO:0000269PubMed:11784712}.

Disease Associations

Tissue Specificity

Expressed at high levels in thymus, lymph node, spleen, fetal kidney and adult testis. Constitutively associated with MPL and EPOR in hematopoietic cells. {ECO:0000269PubMed:11784712}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 30 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Experimentally validated
Total	30 [view]
Protein-Protein	30 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0044822	poly(A) RNA binding

Biological Process

GO:0010603	regulation of cytoplasmic mRNA processing body assembly
GO:0034063	stress granule assembly

Cellular Component

GO:0005737	cytoplasm
GO:0010494	cytoplasmic stress granule
GO:0016020	membrane
GO:0016607	nuclear speck

Protein Structure and Domains

PDB ID

InterPro

PFAM

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q8WWM7

PhosphoSite

PhosphoSite-Q8WWM7

TrEMBL

UniProt Splice Variant

Entrez Gene

11273

UniGene

RefSeq

HUGO

HGNC:31326

OMIM

607931

CCDS

HPRD

06394

IMGT

EMBL

AC116346 AC133550 AC145285 AF034373 AJ317970 AJ317971 AJ317972 AJ317973 AJ317974 AK289981 AY188334 AY188335 AY188336 AY188337 AY188338 BC010239 BC068012 BC082760 BC136584 U70671

GenPept

AAB19201 AAC69607 AAH10239 AAH68012 AAH82760 AAI36585 AAO12056 AAO12057 AAO12058 AAO12059 AAO12060 BAF82670 CAC38068 CAC38069 CAC38070 CAC38071 CAC38072