Version 5.4
Homo sapiens Protein: METRN
Summary
InnateDB Protein IDBP-751605.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol METRN
Protein Name
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000455068
InnateDB Gene IDBG-8135 (METRN)
Protein Structure
UniProt Annotation
Function Involved in both glial cell differentiation and axonal network formation during neurogenesis. Promotes astrocyte differentiation and transforms cerebellar astrocytes into radial glia. Also induces axonal extension in small and intermediate neurons of sensory ganglia by activating nearby satellite glia (By similarity). {ECO:0000250}.
Subcellular Localization Secreted {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0010001 glial cell differentiation
GO:0050772 positive regulation of axonogenesis
Cellular Component
GO:0005615 extracellular space
Protein Structure and Domains
PDB ID
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9UJH8
PhosphoSite PhosphoSite-Q9UJH8
TrEMBL
UniProt Splice Variant
Entrez Gene 79006
UniGene Hs.533772
RefSeq NP_076947
HUGO HGNC:14151
OMIM 610998
CCDS CCDS10422
HPRD 14388
IMGT
EMBL AE006464 BC000662 Z97653
GenPept AAH00662 AAK61247 CAB56188

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca