Version 5.4
Homo sapiens Protein: DEF8
Summary
InnateDB Protein IDBP-753346.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol DEF8
Protein Name
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000456799
InnateDB Gene IDBG-48758 (DEF8)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0008270 zinc ion binding
Biological Process
GO:0035556 intracellular signal transduction
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR002219 Protein kinase C-like, phorbol ester/diacylglycerol-binding domain
PFAM PF00130
PRINTS
PIRSF
SMART SM00109
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q6ZN54
PhosphoSite PhosphoSite-Q6ZN54
TrEMBL H3BNN0
UniProt Splice Variant
Entrez Gene 54849
UniGene Hs.62771
RefSeq NP_001229745
HUGO HGNC:25969
OMIM
CCDS CCDS58495
HPRD 07882
IMGT
EMBL AC092143 AK000193 AK095051 AK096485 AK131370 AK295880 AK296410 AK303510 BC015482 BC105592 CH471184
GenPept AAH15482 AAI05593 BAA91000 BAC04802 BAD18521 BAG52977 BAG59074 BAG64541 BAH12212 EAW66667

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca