InnateDB Protein
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IDBP-758011.3
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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BZRAP1
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Protein Name
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Synonyms
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PBR-IP; PRAX-1; PRAX1; RIM-BP1; RIMBP1;
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000462518
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InnateDB Gene
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IDBG-61001 (BZRAP1)
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Protein Structure
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Function |
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Subcellular Localization |
Cytoplasm {ECO:0000269PubMed:9915832}. Mitochondrion {ECO:0000269PubMed:9915832}. Note=Preferentially expressed in the mitochondria in the presence of BZRP.
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Disease Associations |
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Tissue Specificity |
Predominantly expressed in brain, pituitary gland and thymus in adults. In adult brain, highest expression found in temporal lobe and the putamen, followed by amygdala, caudate nucleus, cerebral cortex, occipital and frontal lobe. A high expression level is also observed in fetal tissues like brain, heart, kidney and thymus. {ECO:0000269PubMed:9915832}.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 21 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
21
[view]
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Protein-Protein |
21
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR001452
SH3 domain
IPR011511
Variant SH3 domain
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PFAM |
PF00018
PF14604
PF07653
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PRINTS |
PR00452
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PIRSF |
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SMART |
SM00326
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TIGRFAMs |
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Modification |
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SwissProt |
O95153
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PhosphoSite |
PhosphoSite-O95153
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
9256
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UniGene |
Hs.713111
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RefSeq |
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HUGO |
HGNC:16831
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OMIM |
610764
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CCDS |
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HPRD |
09832
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IMGT |
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EMBL |
AB014512
AF039571
BC031401
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GenPept |
AAD11957
AAH31401
BAA31587
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