InnateDB Protein
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IDBP-758042.3
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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SLC43A2
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Protein Name
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Synonyms
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000461382
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InnateDB Gene
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IDBG-15005 (SLC43A2)
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Protein Structure
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Function |
Sodium-, chloride-, and pH-independent high affinity transport of large neutral amino acids. {ECO:0000269PubMed:15659399}.
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Subcellular Localization |
Membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
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Disease Associations |
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Tissue Specificity |
Detected in several tissues with higher expression in placenta, kidney and peripheral blood leukocytes. In the kidney, is detected in epithelial cells of the distal tubule and collecting duct. In the intestine, is expressed mainly in crypt cells of the intestinal microvilli and epithelial cells in the base of the villus. {ECO:0000269PubMed:15659399}.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
1
[view]
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Protein-Protein |
1
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
Accession |
GO Term |
GO:0015179
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L-amino acid transmembrane transporter activity
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR011701
Major facilitator superfamily
IPR016196
Major facilitator superfamily domain, general substrate transporter
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PFAM |
PF07690
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q8N370
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PhosphoSite |
PhosphoSite-Q8N370
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
124935
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UniGene |
Hs.160550
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RefSeq |
NP_001271427
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HUGO |
HGNC:23087
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OMIM |
610791
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CCDS |
CCDS67108
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HPRD |
15390
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IMGT |
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EMBL |
AB120364
AC100748
AC130343
AF289592
AK075068
AK075173
AK301127
BC027923
BC071859
BK005642
CH471108
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GenPept |
AAH27923
AAH71859
AAL55776
BAC11383
BAC11450
BAD91091
BAH13415
DAA05676
EAW90602
EAW90604
EAW90605
EAW90607
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