Homo sapiens Protein: TOM1L2
Summary
InnateDB Protein IDBP-758836.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TOM1L2
Protein Name
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000464297
InnateDB Gene IDBG-33308 (TOM1L2)
Protein Structure
UniProt Annotation
Function Probable role in protein transport. May regulate growth factor-induced mitogenic signaling. {ECO:0000269PubMed:16412388, ECO:0000269PubMed:16479011}.
Subcellular Localization
Disease Associations
Tissue Specificity Ubiquitously expressed with higher expression in heart and skeletal muscle. {ECO:0000269PubMed:11997338}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 28 experimentally validated interaction(s) in this database.
Experimentally validated
Total 28 [view]
Protein-Protein 28 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0019901 protein kinase binding
GO:0030276 clathrin binding
Biological Process
GO:0006886 intracellular protein transport
GO:0007165 signal transduction
GO:0045839 negative regulation of mitosis
Cellular Component
GO:0005622 intracellular
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro IPR002014 VHS
IPR004152 GAT
IPR008942 ENTH/VHS
IPR014645 Target of Myb protein 1
IPR018205 VHS subgroup
PFAM PF00790
PF03127
PRINTS
PIRSF PIRSF036948
SMART SM00288
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q6ZVM7
PhosphoSite PhosphoSite-Q6ZVM7
TrEMBL
UniProt Splice Variant
Entrez Gene 146691
UniGene Hs.739326
RefSeq NP_001028723
HUGO HGNC:11984
OMIM 615519
CCDS CCDS32584
HPRD 18213
IMGT
EMBL AC122129 AF467441 AK057308 AK124331 AK301944 BC051650
GenPept AAH51650 AAL78338 BAB71421 BAC85834 BAH13590