Version 5.4
Homo sapiens Protein: ERCC2
Summary
InnateDB Protein IDBP-760404.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ERCC2
Protein Name
Synonyms COFS2; EM9; TFIIH; TTD; XPD;
Species Homo sapiens
Ensembl Protein ENSP00000466998
InnateDB Gene IDBG-57385 (ERCC2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 43 experimentally validated interaction(s) in this database.
Experimentally validated
Total 43 [view]
Protein-Protein 42 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0004003 ATP-dependent DNA helicase activity
GO:0005524 ATP binding
Biological Process
GO:0032508 DNA duplex unwinding
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR010614 DEAD2
IPR014013 Helicase, superfamily 1/2, ATP-binding domain, DinG/Rad3-type
PFAM PF06733
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL K7ENL1
UniProt Splice Variant
Entrez Gene 2068
UniGene Hs.663234
RefSeq
HUGO HGNC:3434
OMIM 126340
CCDS
HPRD 00530
IMGT
EMBL L47234
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca