Version 5.4
Homo sapiens Protein: CCL2
Summary
InnateDB Protein IDBP-762368.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CCL2
Protein Name
Synonyms GDCF-2; HC11; HSMCR30; MCAF; MCP-1; MCP1; SCYA2; SMC-CF;
Species Homo sapiens
Ensembl Protein ENSP00000462156
InnateDB Gene IDBG-40504 (CCL2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 46 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 46 [view]
Protein-Protein 32 [view]
Protein-DNA 12 [view]
Protein-RNA 1 [view]
DNA-DNA 1 [view]
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0008009 chemokine activity
Biological Process
GO:0006955 immune response
GO:0045087 innate immune response (InnateDB)
GO:0060326 cell chemotaxis
Cellular Component
GO:0005576 extracellular region
Protein Structure and Domains
PDB ID
InterPro IPR001811 Chemokine interleukin-8-like domain
PFAM PF00048
PRINTS
PIRSF
SMART SM00199
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q6UZ82
UniProt Splice Variant
Entrez Gene 6347
UniGene Hs.595481
RefSeq
HUGO HGNC:10618
OMIM 158105
CCDS
HPRD 01149
IMGT
EMBL AC005549 AY357296 CH471147 D26087
GenPept AAQ75526 BAA05080 EAW80211

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca