Version 5.4
Homo sapiens Protein: ACTN4
Summary
InnateDB Protein IDBP-764478.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ACTN4
Protein Name
Synonyms ACTININ-4; FSGS; FSGS1;
Species Homo sapiens
Ensembl Protein ENSP00000465176
InnateDB Gene IDBG-49384 (ACTN4)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 91 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.
Experimentally validated
Total 91 [view]
Protein-Protein 91 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 9 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0051015 actin filament binding
Biological Process
GO:0051017 actin filament bundle assembly
GO:0051764 actin crosslink formation
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR001715 Calponin homology domain
IPR002017 Spectrin repeat
PFAM PF00307
PF00435
PRINTS
PIRSF
SMART SM00033
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL K7EJH8
UniProt Splice Variant
Entrez Gene 81
UniGene Hs.667218
RefSeq
HUGO HGNC:166
OMIM 604638
CCDS
HPRD 05222
IMGT
EMBL AC008649 AC022144
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca