Version 5.4
Homo sapiens Protein: VPS26B
Summary
InnateDB Protein IDBP-76486.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol VPS26B
Protein Name vacuolar protein sorting 26 homolog B (S. pombe)
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000281187
InnateDB Gene IDBG-76484 (VPS26B)
Protein Structure
UniProt Annotation
Function Probable component of the retromer complex, a complex required to retrieve lysosomal enzyme receptors (IGF2R and M6PR) from endosomes to the trans-Golgi network. {ECO:0000250}.
Subcellular Localization Cytoplasm. Membrane; Peripheral membrane protein. Note=Does not localize to endosomes. {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
Experimentally validated
Total 6 [view]
Protein-Protein 6 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0015031 protein transport
Cellular Component
GO:0005829 cytosol
GO:0016020 membrane
GO:0043231 intracellular membrane-bounded organelle
Protein Structure and Domains
PDB ID
InterPro IPR014756 Immunoglobulin E-set
IPR028934 Vacuolar protein sorting protein 26 related
PFAM PF03643
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q4G0F5
PhosphoSite PhosphoSite-Q4G0F5
TrEMBL A0A024R3L9
UniProt Splice Variant
Entrez Gene 112936
UniGene Hs.334684
RefSeq NP_443107
HUGO HGNC:28119
OMIM 610027
CCDS CCDS8495
HPRD 14395
IMGT
EMBL AF452718 BC009747 BC014128 BC098386 CH471065
GenPept AAH09747 AAH14128 AAH98386 AAP13353 EAW67825 EAW67826 EAW67827

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca