InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: RDH8

Summary

InnateDB Protein

IDBP-765748.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

RDH8

Protein Name

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000466058

InnateDB Gene

IDBG-26287 (RDH8)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004303	estradiol 17-beta-dehydrogenase activity
GO:0004745	retinol dehydrogenase activity
GO:0016491	oxidoreductase activity
GO:0052650	NADP-retinol dehydrogenase activity

Biological Process

GO:0001523	retinoid metabolic process
GO:0006694	steroid biosynthetic process
GO:0006703	estrogen biosynthetic process
GO:0007601	visual perception
GO:0007603	phototransduction, visible light
GO:0008152	metabolic process
GO:0042572	retinol metabolic process
GO:0055114	oxidation-reduction process

Cellular Component

GO:0005737	cytoplasm
GO:0005887	integral component of plasma membrane

Protein Structure and Domains

PDB ID

InterPro

IPR002198 Short-chain dehydrogenase/reductase SDR
IPR002347 Glucose/ribitol dehydrogenase
IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase
IPR011348 17beta-dehydrogenase
IPR013968 Polyketide synthase, KR

PFAM

PF00106
PF08659

PRINTS

PR00080
PR00081
PR01397

PIRSF

PIRSF000126
PIRSF000095

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt