Version 5.4
Homo sapiens Protein: GTF2F1
Summary
InnateDB Protein IDBP-766099.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol GTF2F1
Protein Name
Synonyms BTF4; RAP74; TF2F1; TFIIF;
Species Homo sapiens
Ensembl Protein ENSP00000469091
InnateDB Gene IDBG-21234 (GTF2F1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 82 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 82 [view]
Protein-Protein 81 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003824 catalytic activity
Biological Process
GO:0006367 transcription initiation from RNA polymerase II promoter
GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter
GO:0045893 positive regulation of transcription, DNA-templated
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID
InterPro IPR008851 Transcription initiation factor IIF, alpha subunit
IPR011039 Transcription Factor IIF, Rap30/Rap74, interaction
PFAM PF05793
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL M0QXD6
UniProt Splice Variant
Entrez Gene 2962
UniGene Hs.68257
RefSeq
HUGO HGNC:4652
OMIM 189968
CCDS
HPRD 01803
IMGT
EMBL AC011491
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca