InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: PRKCSH

Summary

InnateDB Protein

IDBP-766211.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

PRKCSH

Protein Name

Synonyms

AGE-R2; G19P1; PCLD; PKCSH; PLD1;

Species

Homo sapiens

Ensembl Protein

ENSP00000465461

InnateDB Gene

IDBG-29429 (PRKCSH)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 37 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.

Experimentally validated
Total	37 [view]
Protein-Protein	32 [view]
Protein-DNA	5 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	9 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005080	protein kinase C binding
GO:0005509	calcium ion binding
GO:0005515	protein binding
GO:0044325	ion channel binding
GO:0051219	phosphoprotein binding

Biological Process

GO:0006457	protein folding
GO:0006491	N-glycan processing
GO:0018279	protein N-linked glycosylation via asparagine
GO:0035556	intracellular signal transduction
GO:0043687	post-translational protein modification
GO:0044267	cellular protein metabolic process
GO:0045087	innate immune response

Cellular Component

GO:0005622	intracellular
GO:0005783	endoplasmic reticulum
GO:0005788	endoplasmic reticulum lumen

Protein Structure and Domains

PDB ID

InterPro

IPR002048 EF-hand domain
IPR002172 Low-density lipoprotein (LDL) receptor class A repeat
IPR009011 Mannose-6-phosphate receptor binding domain
IPR012913 Glucosidase II beta subunit-like

PFAM

PF00036
PF13202
PF13405
PF00057
PF07915

PRINTS

PR00261

PIRSF

SMART

SM00054
SM00192

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt