Version 5.4
Homo sapiens Protein: PTCH1
Summary
InnateDB Protein IDBP-77106.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PTCH1
Protein Name patched 1
Synonyms BCNS; HPE7; NBCCS; PTC; PTC1; PTCH; PTCH11;
Species Homo sapiens
Ensembl Protein ENSP00000364420
InnateDB Gene IDBG-77092 (PTCH1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 24 experimentally validated interaction(s) in this database.
Experimentally validated
Total 24 [view]
Protein-Protein 22 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0008158 hedgehog receptor activity
Biological Process
GO:0045087 innate immune response (InnateDB)
Cellular Component
GO:0016020 membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR000731 Sterol-sensing domain
IPR003392 Patched
PFAM PF02460
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q3LFT4
UniProt Splice Variant
Entrez Gene 5727
UniGene Hs.494538
RefSeq
HUGO HGNC:9585
OMIM 601309
CCDS
HPRD 03200
IMGT
EMBL AB233422 AL161729
GenPept BAE45302

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca