InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: NAB1

Summary

InnateDB Protein

IDBP-77559.5

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

NAB1

Protein Name

NGFI-A binding protein 1 (EGR1 binding protein 1)

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000336894

InnateDB Gene

IDBG-77557 (NAB1)

Protein Structure

UniProt Annotation

Function

Acts as a transcriptional repressor for zinc finger transcription factors EGR1 and EGR2. {ECO:0000250}.

Subcellular Localization

Nucleus {ECO:0000250}.

Disease Associations

Tissue Specificity

Isoform Short is found in myeloid leukemia cell line KG-1.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Experimentally validated
Total	6 [view]
Protein-Protein	4 [view]
Protein-DNA	1 [view]
Protein-RNA	1 [view]
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0008134	transcription factor binding

Biological Process

GO:0001958	endochondral ossification
GO:0006351	transcription, DNA-templated
GO:0006355	regulation of transcription, DNA-templated
GO:0014037	Schwann cell differentiation
GO:0042552	myelination
GO:0045682	regulation of epidermis development
GO:0045892	negative regulation of transcription, DNA-templated