InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Pak1

Summary

InnateDB Protein

IDBP-788414.1

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Pak1

Protein Name

p21 protein (Cdc42/Rac)-activated kinase 1

Synonyms

AW045634; PAK-1; Paka;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000138684

InnateDB Gene

IDBG-199974 (Pak1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 26 experimentally validated interaction(s) in this database.
They are also associated with 74 interaction(s) predicted by orthology.

Experimentally validated
Total	26 [view]
Protein-Protein	25 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	1 [view]
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	74 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004672	protein kinase activity
GO:0004674	protein serine/threonine kinase activity
GO:0004702	receptor signaling protein serine/threonine kinase activity

Biological Process

GO:0006468	protein phosphorylation
GO:0007409	axonogenesis
GO:0007528	neuromuscular junction development
GO:0016358	dendrite development
GO:0023014	signal transduction by phosphorylation
GO:0030036	actin cytoskeleton organization
GO:0035556	intracellular signal transduction
GO:0043113	receptor clustering

Cellular Component

GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0005925	focal adhesion
GO:0030424	axon
GO:0030426	growth cone

Protein Structure and Domains

PDB ID

MGI:1339975

InterPro

IPR000095 CRIB domain

PFAM

PF00786

PRINTS

PIRSF

SMART

SM00285

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

S4R2K7

UniProt Splice Variant

Entrez Gene

18479

UniGene

RefSeq

MGI ID

MGI Symbol

Pak1

OMIM

CCDS

HPRD

IMGT

EMBL

AC120438 AJ133881

GenPept

CAB41618