Version 5.4
Homo sapiens Protein: COMTD1
Summary
InnateDB Protein IDBP-79505.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol COMTD1
Protein Name catechol-O-methyltransferase domain containing 1
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000361616
InnateDB Gene IDBG-79503 (COMTD1)
Protein Structure
UniProt Annotation
Function Putative O-methyltransferase. {ECO:0000305}.
Subcellular Localization Membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0008171 O-methyltransferase activity
Biological Process
GO:0032259 methylation
Cellular Component
GO:0005739 mitochondrion
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR002935 O-methyltransferase, family 3
IPR029063 S-adenosyl-L-methionine-dependent methyltransferase-like
PFAM PF01596
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q86VU5
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 118881
UniGene
RefSeq NP_653190
HUGO HGNC:26309
OMIM
CCDS CCDS7349
HPRD 08678
IMGT
EMBL AK074421 AL390034 AY358476 BC023663 BC047774
GenPept AAH23663 AAH47774 AAQ88840 BAB85077 CAH73105

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca