InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: AGER

Summary

InnateDB Protein

IDBP-80473.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

AGER

Protein Name

advanced glycosylation end product-specific receptor

Synonyms

RAGE;

Species

Homo sapiens

Ensembl Protein

ENSP00000364206

InnateDB Gene

IDBG-80463 (AGER)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 21 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Experimentally validated
Total	21 [view]
Protein-Protein	21 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004872	receptor activity
GO:0004888	transmembrane signaling receptor activity
GO:0005515	protein binding
GO:0042802	identical protein binding
GO:0044548	S100 protein binding

Biological Process

GO:0006954	inflammatory response
GO:0007166	cell surface receptor signaling pathway
GO:0009611	response to wounding
GO:0031175	neuron projection development
GO:0045087	innate immune response (InnateDB)
GO:0051092	positive regulation of NF-kappaB transcription factor activity