|
InnateDB Protein
|
IDBP-807065.1
|
|
Last Modified
|
2014-10-13 [Report errors or provide feedback]
|
|
Gene Symbol
|
MTHFD1
|
|
Protein Name
|
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase
|
|
Synonyms
|
MTHFC; MTHFD;
|
|
Species
|
Homo sapiens
|
|
Ensembl Protein
|
ENSP00000477199
|
|
InnateDB Gene
|
IDBG-9107 (MTHFD1)
|
|
Protein Structure
|
|
| Function |
|
| Subcellular Localization |
|
| Disease Associations |
|
| Tissue Specificity |
|
| Comments |
|
|
Number of Interactions
|
This gene and/or its encoded proteins are associated with 61 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
| Experimentally validated |
| Total |
61
[view]
|
| Protein-Protein |
54
[view]
|
| Protein-DNA |
7
[view]
|
| Protein-RNA |
0
|
| DNA-DNA |
0
|
| RNA-RNA |
0
|
| DNA-RNA |
0
|
|
| Predicted by orthology |
| Total |
1 [view]
|
|
|
Molecular Function |
|
| Biological Process |
|
GO:0009396
|
folic acid-containing compound biosynthetic process
|
|
| Cellular Component |
|
| PDB ID |
|
| InterPro |
IPR000559
Formate-tetrahydrofolate ligase, FTHFS
IPR027417
P-loop containing nucleoside triphosphate hydrolase
|
| PFAM |
PF01268
|
| PRINTS |
|
| PIRSF |
|
| SMART |
|
| TIGRFAMs |
|
| Modification |
|
| SwissProt |
|
| PhosphoSite |
PhosphoSite-
|
| TrEMBL |
V9GYY3
|
| UniProt Splice Variant |
|
| Entrez Gene |
4522
|
| UniGene |
|
| RefSeq |
|
| HUGO |
HGNC:7432
|
| OMIM |
172460
|
| CCDS |
|
| HPRD |
|
| IMGT |
|
| EMBL |
AL122035
|
| GenPept |
|
|
|
|
Version 5.4