Version 5.4
Homo sapiens Protein: FAS
Summary
InnateDB Protein IDBP-807194.1
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol FAS
Protein Name Fas cell surface death receptor
Synonyms ALPS1A; APO-1; APT1; CD95; FAS1; FASTM; TNFRSF6;
Species Homo sapiens
Ensembl Protein ENSP00000484575
InnateDB Gene IDBG-81669 (FAS)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 123 experimentally validated interaction(s) in this database.
They are also associated with 12 interaction(s) predicted by orthology.
Experimentally validated
Total 123 [view]
Protein-Protein 109 [view]
Protein-DNA 10 [view]
Protein-RNA 3 [view]
DNA-DNA 1 [view]
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 12 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR001368 TNFR/NGFR cysteine-rich region
IPR008063 Fas receptor
IPR011029 Death-like domain
PFAM PF00020
PRINTS PR01680
PIRSF
SMART SM00208
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL E6Y7C3
UniProt Splice Variant
Entrez Gene 355
UniGene
RefSeq
HUGO HGNC:11920
OMIM 134637
CCDS
HPRD
IMGT
EMBL FJ373045
GenPept ACP28876

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca