Version 5.4
Homo sapiens Protein: MSH6
Summary
InnateDB Protein IDBP-808396.1
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MSH6
Protein Name mutS homolog 6
Synonyms GTBP; GTMBP; HNPCC5; HSAP; p160;
Species Homo sapiens
Ensembl Protein ENSP00000482078
InnateDB Gene IDBG-51044 (MSH6)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 86 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Experimentally validated
Total 88 [view]
Protein-Protein 85 [view]
Protein-DNA 3 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005524 ATP binding
GO:0030983 mismatched DNA binding
Biological Process
GO:0006298 mismatch repair
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR000432 DNA mismatch repair protein MutS, C-terminal
IPR007696 DNA mismatch repair protein MutS, core
IPR027417 P-loop containing nucleoside triphosphate hydrolase
PFAM PF00488
PF05192
PRINTS
PIRSF
SMART SM00534
SM00533
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 2956
UniGene
RefSeq
HUGO HGNC:7329
OMIM 600678
CCDS
HPRD
IMGT
EMBL
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca