InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: RECQL4

Summary

InnateDB Protein

IDBP-808909.1

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

RECQL4

Protein Name

RecQ protein-like 4

Synonyms

RECQ4;

Species

Homo sapiens

Ensembl Protein

ENSP00000482313

InnateDB Gene

IDBG-41326 (RECQL4)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 21 experimentally validated interaction(s) in this database.

Experimentally validated
Total	21 [view]
Protein-Protein	16 [view]
Protein-DNA	5 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003676	nucleic acid binding
GO:0005524	ATP binding
GO:0008026	ATP-dependent helicase activity
GO:0008270	zinc ion binding

Biological Process

GO:0001501	skeletal system development
GO:0006200	ATP catabolic process
GO:0006310	DNA recombination
GO:0008284	positive regulation of cell proliferation
GO:0043473	pigmentation
GO:0045875	negative regulation of sister chromatid cohesion
GO:0048705	skeletal system morphogenesis

Cellular Component

Protein Structure and Domains

PDB ID

InterPro

IPR001650 Helicase, C-terminal
IPR004589 DNA helicase, ATP-dependent, RecQ type
IPR011545 DEAD/DEAH box helicase domain
IPR014001 Helicase, superfamily 1/2, ATP-binding domain
IPR021110 DNA replication/checkpoint protein
IPR027417 P-loop containing nucleoside triphosphate hydrolase

PFAM

PF00271
PF00270
PF11719

PRINTS

PIRSF

SMART

SM00490
SM00487

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite