InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: LAP3

Summary

InnateDB Protein

IDBP-809783.1

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

LAP3

Protein Name

leucine aminopeptidase 3

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000481000

InnateDB Gene

IDBG-10959 (LAP3)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 25 experimentally validated interaction(s) in this database.

Experimentally validated
Total	25 [view]
Protein-Protein	25 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004177	aminopeptidase activity
GO:0008235	metalloexopeptidase activity
GO:0030145	manganese ion binding

Biological Process

GO:0006508

proteolysis

Cellular Component

GO:0005622	intracellular
GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0070062	extracellular vesicular exosome

Protein Structure and Domains

PDB ID

InterPro

IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal
IPR008283 Peptidase M17, leucyl aminopeptidase, N-terminal
IPR011356 Leucine aminopeptidase/peptidase B

PFAM

PF00883
PF02789

PRINTS

PR00481

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

UniProt Splice Variant

Entrez Gene

51056

UniGene

RefSeq

NP_056991

HUGO

HGNC:18449

OMIM

170250

CCDS

CCDS3422

HPRD

IMGT

EMBL

AF061738 AK022055 AK298613 BC006199 BC065564 CR457128

GenPept

AAD17527 AAH06199 AAH65564 BAG51065 BAG60795 CAG33409