InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: CLN5

Summary

InnateDB Protein

IDBP-810471.1

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

CLN5

Protein Name

ceroid-lipofuscinosis, neuronal 5

Synonyms

NCL;

Species

Homo sapiens

Ensembl Protein

ENSP00000479547

InnateDB Gene

IDBG-39320 (CLN5)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 37 experimentally validated interaction(s) in this database.

Experimentally validated
Total	37 [view]
Protein-Protein	36 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0005537	mannose binding

Biological Process

GO:0006465	signal peptide processing
GO:0007042	lysosomal lumen acidification
GO:0007420	brain development
GO:0008219	cell death
GO:0022008	neurogenesis
GO:0030163	protein catabolic process
GO:0042551	neuron maturation
GO:0070085	glycosylation

Cellular Component

GO:0005764	lysosome
GO:0005765	lysosomal membrane
GO:0005783	endoplasmic reticulum
GO:0005794	Golgi apparatus
GO:0016021	integral component of membrane
GO:0048471	perinuclear region of cytoplasm

Protein Structure and Domains

PDB ID

InterPro

PFAM

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

B4E1V6

UniProt Splice Variant

Entrez Gene

1203

UniGene

RefSeq

HUGO

HGNC:2076

OMIM

608102

CCDS

HPRD

IMGT

EMBL

AC001226 AF068227 AK075109 AK304001

GenPept

AAC27614 BAG52069 BAG64918