Version 5.4
Homo sapiens Protein: SOCS7
Summary
InnateDB Protein IDBP-810554.1
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SOCS7
Protein Name suppressor of cytokine signaling 7
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000482229
InnateDB Gene IDBG-775508 (SOCS7)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 14 experimentally validated interaction(s) in this database.
Experimentally validated
Total 14 [view]
Protein-Protein 13 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 1 [view]
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0017124 SH3 domain binding
Biological Process
GO:0008150 biological_process
GO:0008286 insulin receptor signaling pathway
GO:0009968 negative regulation of signal transduction
GO:0016567 protein ubiquitination
GO:0035556 intracellular signal transduction
GO:0040008 regulation of growth
GO:0045444 fat cell differentiation
Cellular Component
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0043231 intracellular membrane-bounded organelle
Protein Structure and Domains
PDB ID
InterPro IPR000980 SH2 domain
IPR001496 SOCS protein, C-terminal
PFAM PF00017
PF14633
PF07525
PRINTS PR00401
PIRSF
SMART SM00252
SM00253
SM00969
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt O14512
PhosphoSite PhosphoSite-O14512
TrEMBL
UniProt Splice Variant
Entrez Gene 30837
UniGene
RefSeq NP_055413
HUGO HGNC:29846
OMIM 608788
CCDS CCDS32637
HPRD
IMGT
EMBL AB005216 AC115992 AC124789 BC128607
GenPept AAI28608 BAA22432

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca