Version 5.4
Homo sapiens Protein: BOP1
Summary
InnateDB Protein IDBP-810600.1
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BOP1
Protein Name block of proliferation 1
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000455106
InnateDB Gene IDBG-775503 (BOP1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 35 experimentally validated interaction(s) in this database.
Experimentally validated
Total 35 [view]
Protein-Protein 35 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0043021 ribonucleoprotein complex binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0000448 cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000466 maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0006364 rRNA processing
GO:0008283 cell proliferation
GO:0042254 ribosome biogenesis
GO:0042273 ribosomal large subunit biogenesis
GO:0051726 regulation of cell cycle
Cellular Component
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0030529 ribonucleoprotein complex
GO:0030687 preribosome, large subunit precursor
GO:0070545 PeBoW complex
Protein Structure and Domains
PDB ID
InterPro IPR001680 WD40 repeat
IPR012953 BOP1, N-terminal domain
IPR017986 WD40-repeat-containing domain
PFAM PF00400
PF08145
PRINTS
PIRSF
SMART SM00320
SM01035
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q14137
PhosphoSite PhosphoSite-Q14137
TrEMBL Q96Q25
UniProt Splice Variant
Entrez Gene 23246
UniGene
RefSeq NP_056016
HUGO HGNC:15519
OMIM 610596
CCDS CCDS6418
HPRD
IMGT
EMBL AB060694 AC110280 AC145291 AC231662 BC001086 BC005160 BC007274 BC013787 BC013980 BC017674 BC073813 BC098446 D50914
GenPept AAH01086 AAH05160 AAH07274 AAH13787 AAH13980 AAH17674 AAH73813 AAH98446 BAA09473 BAB70666

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca