Homo sapiens Protein: CIB1
Summary
InnateDB Protein IDBP-811406.1
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CIB1
Protein Name calcium and integrin binding 1 (calmyrin)
Synonyms CIB; CIBP; KIP1; PRKDCIP; SIP2-28;
Species Homo sapiens
Ensembl Protein ENSP00000479860
InnateDB Gene IDBG-29930 (CIB1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 35 experimentally validated interaction(s) in this database.
Experimentally validated
Total 35 [view]
Protein-Protein 31 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 2 [view]
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0044325 ion channel binding
Biological Process
GO:0001933 negative regulation of protein phosphorylation
GO:0001934 positive regulation of protein phosphorylation
GO:0001954 positive regulation of cell-matrix adhesion
GO:0002931 response to ischemia
GO:0007286 spermatid development
GO:0008284 positive regulation of cell proliferation
GO:0030220 platelet formation
GO:0030307 positive regulation of cell growth
GO:0030335 positive regulation of cell migration
GO:0038163 thrombopoietin-mediated signaling pathway
GO:0043066 negative regulation of apoptotic process
GO:0045653 negative regulation of megakaryocyte differentiation
GO:0048554 positive regulation of metalloenzyme activity
GO:0051898 negative regulation of protein kinase B signaling
GO:0070374 positive regulation of ERK1 and ERK2 cascade
GO:0070886 positive regulation of calcineurin-NFAT signaling cascade
GO:0071363 cellular response to growth factor stimulus
GO:0071902 positive regulation of protein serine/threonine kinase activity
GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis
GO:1901313 positive regulation of gene expression involved in extracellular matrix organization
GO:2000256 positive regulation of male germ cell proliferation
Cellular Component
GO:0005737 cytoplasm
GO:0016020 membrane
Protein Structure and Domains
PDB ID
InterPro IPR002048 EF-hand domain
PFAM PF00036
PF13202
PF13405
PRINTS
PIRSF
SMART SM00054
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 10519
UniGene
RefSeq NP_001264693
HUGO HGNC:16920
OMIM 602293
CCDS CCDS73781
HPRD
IMGT
EMBL
GenPept