InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: ATP9A

Summary

InnateDB Protein

IDBP-81264.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

ATP9A

Protein Name

ATPase, class II, type 9A

Synonyms

ATPIIA;

Species

Homo sapiens

Ensembl Protein

ENSP00000342481

InnateDB Gene

IDBG-81258 (ATP9A)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Early endosome membrane {ECO:0000269PubMed:21914794}; Multi-pass membrane protein {ECO:0000269PubMed:21914794}. Recycling endosome {ECO:0000269PubMed:21914794}. Golgi apparatus, trans-Golgi network membrane {ECO:0000269PubMed:21914794}. Note=Efficient exit from the endoplasmic reticulum does not require TMEM30A, nor TMEM30B.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.

Experimentally validated
Total	3 [view]
Protein-Protein	3 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000166	nucleotide binding
GO:0000287	magnesium ion binding
GO:0004012	phospholipid-translocating ATPase activity
GO:0005524	ATP binding
GO:0019829	cation-transporting ATPase activity
GO:0046872	metal ion binding

Biological Process

GO:0006812	cation transport
GO:0008152	metabolic process
GO:0015914	phospholipid transport
GO:0045332	phospholipid translocation

Cellular Component

GO:0005769	early endosome
GO:0005802	trans-Golgi network
GO:0016021	integral component of membrane
GO:0031901	early endosome membrane
GO:0048471	perinuclear region of cytoplasm
GO:0055037	recycling endosome

Protein Structure and Domains

PDB ID

InterPro

IPR001757 Cation-transporting P-type ATPase
IPR006539 Cation-transporting P-type ATPase, subfamily IV
IPR008250 P-type ATPase, A domain
IPR023214 HAD-like domain
IPR023299 P-type ATPase, cytoplasmic domain N

PFAM

PF00122
PF00702
PF08282
PF13419

PRINTS

PR00119
PR00120

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

O75110