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InnateDB Protein
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IDBP-813399.1
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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PITX2
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Protein Name
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paired-like homeodomain 2
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Synonyms
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ARP1; Brx1; IDG2; IGDS; IGDS2; IHG2; IRID2; Otlx2; PTX2; RGS; RIEG; RIEG1; RS;
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000475617
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InnateDB Gene
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IDBG-34290 (PITX2)
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Protein Structure
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| Function |
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| Subcellular Localization |
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| Disease Associations |
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| Tissue Specificity |
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| Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 19 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
| Experimentally validated |
| Total |
19
[view]
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| Protein-Protein |
18
[view]
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| Protein-DNA |
0
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| Protein-RNA |
0
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| DNA-DNA |
1
[view]
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| RNA-RNA |
0
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| DNA-RNA |
0
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| Predicted by orthology |
| Total |
6 [view]
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Molecular Function |
| Accession |
GO Term |
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GO:0003677
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DNA binding
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GO:0003700
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sequence-specific DNA binding transcription factor activity
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GO:0043565
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sequence-specific DNA binding
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| Biological Process |
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GO:0006355
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regulation of transcription, DNA-templated
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| Cellular Component |
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| PDB ID |
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| InterPro |
IPR001356
Homeobox domain
IPR009057
Homeodomain-like
IPR016233
Homeobox protein Pitx/unc30
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| PFAM |
PF00046
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| PRINTS |
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| PIRSF |
PIRSF000563
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| SMART |
SM00389
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| TIGRFAMs |
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| Modification |
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| SwissProt |
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| PhosphoSite |
PhosphoSite-
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| TrEMBL |
U3KQ81
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| UniProt Splice Variant |
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| Entrez Gene |
5308
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| UniGene |
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| RefSeq |
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| HUGO |
HGNC:9005
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| OMIM |
601542
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| CCDS |
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| HPRD |
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| IMGT |
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| EMBL |
AC017068
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| GenPept |
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Version 5.4