Homo sapiens Protein: KANK1
Summary
InnateDB Protein IDBP-813455.1
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol KANK1
Protein Name KN motif and ankyrin repeat domains 1
Synonyms ANKRD15; CPSQ2; KANK;
Species Homo sapiens
Ensembl Protein ENSP00000477725
InnateDB Gene IDBG-43688 (KANK1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 10 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 10 [view]
Protein-Protein 10 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008013 beta-catenin binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0010977 negative regulation of neuron projection development
GO:0030177 positive regulation of Wnt signaling pathway
GO:0030336 negative regulation of cell migration
GO:0030837 negative regulation of actin filament polymerization
GO:0035024 negative regulation of Rho protein signal transduction
GO:0035413 positive regulation of catenin import into nucleus
GO:0046627 negative regulation of insulin receptor signaling pathway
GO:0090303 positive regulation of wound healing
GO:1900025 negative regulation of substrate adhesion-dependent cell spreading
GO:1900028 negative regulation of ruffle assembly
GO:2000114 regulation of establishment of cell polarity
GO:2000393 negative regulation of lamellipodium morphogenesis
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0032587 ruffle membrane
Protein Structure and Domains
PDB ID
InterPro IPR002110 Ankyrin repeat
IPR020683 Ankyrin repeat-containing domain
IPR021939 Kank N-terminal motif
PFAM PF00023
PF13606
PF11929
PF12796
PF12075
PRINTS PR01415
PIRSF
SMART SM00248
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q8WUM7
UniProt Splice Variant
Entrez Gene 23189
UniGene
RefSeq NP_001243806
HUGO HGNC:19309
OMIM 607704
CCDS CCDS34976
HPRD
IMGT
EMBL AB205106 AB205107 AB205108 AB205109 AB205110 AL136979 BC020040 BC037495 CH471071 D79994
GenPept AAH20040 AAH37495 BAA11489 BAD97395 BAD97396 BAD97397 BAD97398 BAD97399 CAH70388 CAM13084 EAW58821 EAW58822