InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: FARSB

Summary

InnateDB Protein

IDBP-82210.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

FARSB

Protein Name

phenylalanyl-tRNA synthetase, beta subunit

Synonyms

FARSLB; FRSB; PheHB; PheRS;

Species

Homo sapiens

Ensembl Protein

ENSP00000281828

InnateDB Gene

IDBG-82208 (FARSB)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Cytoplasm {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 36 experimentally validated interaction(s) in this database.

Experimentally validated
Total	36 [view]
Protein-Protein	35 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000166	nucleotide binding
GO:0000287	magnesium ion binding
GO:0003723	RNA binding
GO:0004826	phenylalanine-tRNA ligase activity
GO:0005524	ATP binding

Biological Process

GO:0006412	translation
GO:0006418	tRNA aminoacylation for protein translation
GO:0006432	phenylalanyl-tRNA aminoacylation
GO:0010467	gene expression

Cellular Component

GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0016020	membrane

Protein Structure and Domains

PDB ID

InterPro

IPR004531 Phenylalanyl-tRNA synthetase, class IIc, beta subunit, archae/euk cytosolic
IPR005146 B3/B4 tRNA-binding domain
IPR005147 tRNA synthetase, B5-domain
IPR009061 DNA binding domain, putative
IPR020825 Phenylalanyl-tRNA synthetase, B3/B4

PFAM

PF03483
PF03484

PRINTS

PIRSF

SMART

SM00873
SM00874

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q9NSD9