InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: FGF20

Summary

InnateDB Protein

IDBP-8429.4

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

FGF20

Protein Name

fibroblast growth factor 20

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000180166

InnateDB Gene

IDBG-8423 (FGF20)

Protein Structure

UniProt Annotation

Function

Neurotrophic factor that regulates central nervous development and function. {ECO:0000269PubMed:16597617}.

Subcellular Localization

Secreted {ECO:0000269PubMed:11306498}.

Disease Associations

Tissue Specificity

Predominantly expressed in the cerebellum. {ECO:0000269PubMed:11306498}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005104	fibroblast growth factor receptor binding
GO:0008083	growth factor activity

Biological Process

GO:0007165	signal transduction
GO:0007173	epidermal growth factor receptor signaling pathway
GO:0007267	cell-cell signaling
GO:0008284	positive regulation of cell proliferation
GO:0008286	insulin receptor signaling pathway
GO:0008543	fibroblast growth factor receptor signaling pathway
GO:0030154	cell differentiation
GO:0038095	Fc-epsilon receptor signaling pathway
GO:0045087	innate immune response
GO:0048011	neurotrophin TRK receptor signaling pathway
GO:0048015	phosphatidylinositol-mediated signaling
GO:0060043	regulation of cardiac muscle cell proliferation
GO:0060113	inner ear receptor cell differentiation
GO:0070374	positive regulation of ERK1 and ERK2 cascade