Version 5.4
Homo sapiens Protein: FRAT2
Summary
InnateDB Protein IDBP-84540.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol FRAT2
Protein Name frequently rearranged in advanced T-cell lymphomas 2
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000360058
InnateDB Gene IDBG-84538 (FRAT2)
Protein Structure
UniProt Annotation
Function Positively regulates the Wnt signaling pathway by stabilizing beta-catenin through the association with GSK-3.
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
Biological Process
GO:0007275 multicellular organismal development
GO:0008283 cell proliferation
GO:0016055 Wnt signaling pathway
Cellular Component
GO:0005575 cellular_component
Protein Structure and Domains
PDB ID
InterPro IPR008014 Glycogen synthase kinase-3 binding protein
PFAM PF05350
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt O75474
PhosphoSite PhosphoSite-O75474
TrEMBL
UniProt Splice Variant
Entrez Gene 23401
UniGene Hs.140720
RefSeq NP_036215
HUGO HGNC:16048
OMIM 605006
CCDS CCDS7456
HPRD 05419
IMGT
EMBL AB045118 AF062739 AL355490 BC020165
GenPept AAC39786 AAH20165 BAB39165 CAI40774

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca