Version 5.4
Homo sapiens Protein: MIOS
Summary
InnateDB Protein IDBP-8506.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MIOS
Protein Name missing oocyte, meiosis regulator, homolog (Drosophila)
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000339881
InnateDB Gene IDBG-8504 (MIOS)
Protein Structure
UniProt Annotation
Function As a component of the GATOR2 complex, inhibits GATOR1 complex, an inhibitor of the amino acid-sensing branch of the TORC1 pathway.
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
Cellular Component
GO:0005765 lysosomal membrane
Protein Structure and Domains
PDB ID
InterPro IPR001680 WD40 repeat
PFAM PF00400
PRINTS
PIRSF
SMART SM00320
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9NXC5
PhosphoSite PhosphoSite-Q9NXC5
TrEMBL C9JUE6
UniProt Splice Variant
Entrez Gene 54468
UniGene Hs.630761
RefSeq NP_061878
HUGO HGNC:21905
OMIM 615359
CCDS CCDS43554
HPRD 07898
IMGT
EMBL AC004982 AK000330 AL136892 BC005883 BC140833 BC140834 CH471073
GenPept AAC31788 AAH05883 AAI40834 AAI40835 BAA91090 CAB66826 EAW93598 EAW93599 EAW93601

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca