InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: PBX3

Summary

InnateDB Protein

IDBP-85331.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

PBX3

Protein Name

pre-B-cell leukemia homeobox 3

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000362588

InnateDB Gene

IDBG-85327 (PBX3)

Protein Structure

UniProt Annotation

Function

Transcriptional activator that binds the sequence 5'- ATCAATCAA-3'.

Subcellular Localization

Nucleus {ECO:0000305}.

Disease Associations

Tissue Specificity

Ubiquitously expressed.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
They are also associated with 16 interaction(s) predicted by orthology.

Experimentally validated
Total	6 [view]
Protein-Protein	6 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	16 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003677	DNA binding
GO:0003700	sequence-specific DNA binding transcription factor activity
GO:0005515	protein binding
GO:0043565	sequence-specific DNA binding

Biological Process

GO:0002087	regulation of respiratory gaseous exchange by neurological system process
GO:0006351	transcription, DNA-templated
GO:0006355	regulation of transcription, DNA-templated
GO:0007387	anterior compartment pattern formation
GO:0007388	posterior compartment specification
GO:0007585	respiratory gaseous exchange
GO:0008344	adult locomotory behavior
GO:0021516	dorsal spinal cord development
GO:0048666	neuron development