Version 5.4
Homo sapiens Protein: TBC1D22B
Summary
InnateDB Protein IDBP-85595.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TBC1D22B
Protein Name TBC1 domain family, member 22B
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000362590
InnateDB Gene IDBG-85593 (TBC1D22B)
Protein Structure
UniProt Annotation
Function May act as a GTPase-activating protein for Rab family protein(s). {ECO:0000250}.
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005097 Rab GTPase activator activity
Biological Process
GO:0032313 regulation of Rab GTPase activity
GO:0032851 positive regulation of Rab GTPase activity
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR000195 Rab-GTPase-TBC domain
PFAM PF00566
PRINTS
PIRSF
SMART SM00164
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9NU19
PhosphoSite PhosphoSite-Q9NU19
TrEMBL
UniProt Splice Variant
Entrez Gene 55633
UniGene
RefSeq NP_060242
HUGO HGNC:21602
OMIM
CCDS CCDS4832
HPRD 15475
IMGT
EMBL AB449909 AK000344 AK292893 AL096712 AL353579 AL589667 AY313781 BC000291 BC000743 BC001927 BC002720 BC063523 BC109026 BC109027 CH471081
GenPept AAH00291 AAH00743 AAH01927 AAH02720 AAH63523 AAI09027 AAI09028 AAQ72548 BAA91099 BAF85582 BAH16652 CAH71194 CAI20318 CAI22620 EAX03939

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca