Version 5.4
Homo sapiens Protein: SNAPC1
Summary
InnateDB Protein IDBP-8575.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SNAPC1
Protein Name small nuclear RNA activating complex, polypeptide 1, 43kDa
Synonyms PTFgamma; SNAP43;
Species Homo sapiens
Ensembl Protein ENSP00000216294
InnateDB Gene IDBG-8573 (SNAPC1)
Protein Structure
UniProt Annotation
Function Part of the SNAPc complex required for the transcription of both RNA polymerase II and III small-nuclear RNA genes. Binds to the proximal sequence element (PSE), a non-TATA-box basal promoter element common to these 2 types of genes. Recruits TBP and BRF2 to the U6 snRNA TATA box. {ECO:0000269PubMed:12621023}.
Subcellular Localization Nucleus.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 17 experimentally validated interaction(s) in this database.
Experimentally validated
Total 17 [view]
Protein-Protein 13 [view]
Protein-DNA 3 [view]
Protein-RNA 0
DNA-DNA 1 [view]
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
Biological Process
GO:0006355 regulation of transcription, DNA-templated
GO:0006383 transcription from RNA polymerase III promoter
GO:0010467 gene expression
Cellular Component
GO:0005654 nucleoplasm
Protein Structure and Domains
PDB ID
InterPro IPR019188 Small nuclear RNA activating complex (SNAPc), subunit SNAP43
PFAM PF09808
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q16533
PhosphoSite PhosphoSite-Q16533
TrEMBL
UniProt Splice Variant
Entrez Gene 6617
UniGene Hs.603981
RefSeq NP_003073
HUGO HGNC:11134
OMIM 600591
CCDS CCDS9755
HPRD 08998
IMGT
EMBL BC014984 BC019038 U44754 Z47542
GenPept AAC50358 AAH14984 AAH19038 CAA87590

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca