Version 5.4
Homo sapiens Protein: BHLHE23
Summary
InnateDB Protein IDBP-85797.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BHLHE23
Protein Name basic helix-loop-helix family, member e23
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000359371
InnateDB Gene IDBG-85795 (BHLHE23)
Protein Structure
UniProt Annotation
Function May function as transcriptional repressor. May modulate the expression of genes required for the differentiation and/or maintenance of pancreatic and neuronal cell types. May be important for rod bipolar cell maturation (By similarity). {ECO:0000250}.
Subcellular Localization Nucleus {ECO:0000305}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0046983 protein dimerization activity
Biological Process
GO:0006351 transcription, DNA-templated
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID
InterPro IPR011598 Myc-type, basic helix-loop-helix (bHLH) domain
PFAM PF00010
PRINTS
PIRSF
SMART SM00353
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8NDY6
PhosphoSite PhosphoSite-Q8NDY6
TrEMBL
UniProt Splice Variant
Entrez Gene 128408
UniGene Hs.551230
RefSeq
HUGO HGNC:16093
OMIM 609331
CCDS
HPRD 16550
IMGT
EMBL AL121673 BC137288 BC137308 BK000274 CH471077
GenPept AAI37289 AAI37309 CAD37449 DAA01054 EAW75311

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca