InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: KCNQ2

Summary

InnateDB Protein

IDBP-86074.5

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

KCNQ2

Protein Name

potassium voltage-gated channel, KQT-like subfamily, member 2

Synonyms

BFNC; BFNS1; EBN; EBN1; EIEE7; ENB1; HNSPC; KCNA11; KV7.2; KVEBN1;

Species

Homo sapiens

Ensembl Protein

ENSP00000359244

InnateDB Gene

IDBG-86058 (KCNQ2)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Experimentally validated
Total	5 [view]
Protein-Protein	5 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005216	ion channel activity
GO:0005249	voltage-gated potassium channel activity
GO:0005267	potassium channel activity

Biological Process

GO:0006811	ion transport
GO:0055085	transmembrane transport
GO:0071805	potassium ion transmembrane transport

Cellular Component

GO:0008076	voltage-gated potassium channel complex
GO:0016020	membrane

Protein Structure and Domains

PDB ID

InterPro

IPR003091 Potassium channel
IPR003937 Potassium channel, voltage dependent, KCNQ
IPR003947 Potassium channel, voltage dependent, KCNQ2
IPR005821 Ion transport domain
IPR013099 Two pore domain potassium channel domain
IPR013821 Potassium channel, voltage dependent, KCNQ, C-terminal
IPR020969 Ankyrin-G binding site

PFAM

PF00520
PF07885
PF03520
PF11956

PRINTS

PR00169
PR01459
PR01461

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite