Version 5.4
Homo sapiens Protein: SEC31B
Summary
InnateDB Protein IDBP-86528.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SEC31B
Protein Name SEC31 homolog B (S. cerevisiae)
Synonyms SEC31B-1; SEC31L2;
Species Homo sapiens
Ensembl Protein ENSP00000359370
InnateDB Gene IDBG-86526 (SEC31B)
Protein Structure
UniProt Annotation
Function As a component of the coat protein complex II (COPII), may function in vesicle budding and cargo export from the endoplasmic reticulum. {ECO:0000269PubMed:16495487}.
Subcellular Localization Cytoplasm {ECO:0000269PubMed:16495487}. Cytoplasmic vesicle, COPII-coated vesicle membrane {ECO:0000269PubMed:16495487}; Peripheral membrane protein {ECO:0000269PubMed:16495487}; Cytoplasmic side {ECO:0000269PubMed:16495487}. Endoplasmic reticulum membrane {ECO:0000269PubMed:16495487}; Peripheral membrane protein {ECO:0000269PubMed:16495487}.
Disease Associations
Tissue Specificity Ubiquitously expressed at low levels with specific expression in thymus and testis. Expressed in testis by Sertoli cells, Leydig cells and spermatogonia and in cerebellum more prominently by Purkinje and granular cells (at protein level). {ECO:0000269PubMed:10788476, ECO:0000269PubMed:16495487}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0015031 protein transport
GO:0016192 vesicle-mediated transport
Cellular Component
GO:0005789 endoplasmic reticulum membrane
GO:0012507 ER to Golgi transport vesicle membrane
GO:0030120 vesicle coat
Protein Structure and Domains
PDB ID
InterPro IPR001680 WD40 repeat
IPR017986 WD40-repeat-containing domain
PFAM PF00400
PRINTS
PIRSF
SMART SM00320
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9NQW1
PhosphoSite PhosphoSite-Q9NQW1
TrEMBL
UniProt Splice Variant
Entrez Gene 25956
UniGene Hs.18889
RefSeq NP_056305
HUGO HGNC:23197
OMIM 610258
CCDS CCDS7495
HPRD 15315
IMGT
EMBL AF274863 AL080141 AL133352 BC034946 BC044569 BC144313 BX640914
GenPept AAF78243 AAH34946 AAI44314 CAB45735 CAE45955 CAH73561

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca