InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: AK1

Summary

InnateDB Protein

IDBP-86693.5

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

AK1

Protein Name

adenylate kinase 1

Synonyms

HTL-S-58j;

Species

Homo sapiens

Ensembl Protein

ENSP00000223836

InnateDB Gene

IDBG-86687 (AK1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 10 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Experimentally validated
Total	10 [view]
Protein-Protein	10 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004017	adenylate kinase activity
GO:0004550	nucleoside diphosphate kinase activity
GO:0005524	ATP binding
GO:0016301	kinase activity

Biological Process

GO:0006165	nucleoside diphosphate phosphorylation
GO:0006172	ADP biosynthetic process
GO:0009142	nucleoside triphosphate biosynthetic process
GO:0046033	AMP metabolic process
GO:0046034	ATP metabolic process

Cellular Component

GO:0005737

cytoplasm

Protein Structure and Domains

PDB ID

InterPro

IPR000850 Adenylate kinase/UMP-CMP kinase
IPR006267 Adenylate kinase, isozyme 1/5
IPR010488 Zeta toxin domain
IPR027417 P-loop containing nucleoside triphosphate hydrolase

PFAM

PF06414

PRINTS

PR00094

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite