Version 5.4
Homo sapiens Protein: CERCAM
Summary
InnateDB Protein IDBP-88035.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CERCAM
Protein Name cerebral endothelial cell adhesion molecule
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000361929
InnateDB Gene IDBG-88029 (CERCAM)
Protein Structure
UniProt Annotation
Function Probable cell adhesion protein involved in leukocyte transmigration across the blood-brain barrier. Has apparently no beta-galactosyltransferase activity. {ECO:0000269PubMed:10608765, ECO:0000269PubMed:19075007}.
Subcellular Localization Endoplasmic reticulum lumen {ECO:0000255PROSITE-ProRule:PRU10138}.
Disease Associations
Tissue Specificity Ubiquitous. Highly expressed in secretory and nervous tissues. {ECO:0000269PubMed:10608765, ECO:0000269PubMed:19075007}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0006928 cellular component movement
GO:0007155 cell adhesion
GO:0007159 leukocyte cell-cell adhesion
GO:0009103 lipopolysaccharide biosynthetic process
Cellular Component
GO:0005788 endoplasmic reticulum lumen
GO:0005886 plasma membrane
Protein Structure and Domains
PDB ID
InterPro IPR002654 Glycosyl transferase, family 25
IPR029044 Nucleotide-diphospho-sugar transferases
PFAM PF01755
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q5T4B2
PhosphoSite PhosphoSite-Q5T4B2
TrEMBL B7ZBT0
UniProt Splice Variant
Entrez Gene 51148
UniGene Hs.495230
RefSeq NP_057258
HUGO HGNC:23723
OMIM
CCDS CCDS6901
HPRD 16705
IMGT
EMBL AB040935 AF177203 AK074519 AK074523 AL359091 BC011811 BC098432 BC108698 BC119698 BC119699 CH471090
GenPept AAD51367 AAH11811 AAH98432 AAI08699 AAI19699 AAI19700 BAA96026 BAC11036 BAC11040 CAI13494 CAI13495 CAI13496 EAW87787 EAW87789

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca