InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: ACTR1A

Summary

InnateDB Protein

IDBP-88049.5

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

ACTR1A

Protein Name

ARP1 actin-related protein 1 homolog A, centractin alpha (yeast)

Synonyms

ARP1; CTRN1;

Species

Homo sapiens

Ensembl Protein

ENSP00000358921

InnateDB Gene

IDBG-88047 (ACTR1A)

Protein Structure

UniProt Annotation

Function

Component of a multi-subunit complex involved in microtubule based vesicle motility. It is associated with the centrosome.

Subcellular Localization

Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 41 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.

Experimentally validated
Total	41 [view]
Protein-Protein	39 [view]
Protein-DNA	2 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	3 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005524	ATP binding

Biological Process

GO:0000086	G2/M transition of mitotic cell cycle
GO:0000278	mitotic cell cycle
GO:0016192	vesicle-mediated transport
GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II

Cellular Component

GO:0005737	cytoplasm
GO:0005813	centrosome
GO:0005829	cytosol
GO:0005856	cytoskeleton
GO:0005869	dynactin complex
GO:0005875	microtubule associated complex
GO:0070062	extracellular vesicular exosome