Version 5.4
Homo sapiens Protein: IDH3G
Summary
InnateDB Protein IDBP-89981.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol IDH3G
Protein Name isocitrate dehydrogenase 3 (NAD+) gamma
Synonyms H-IDHG;
Species Homo sapiens
Ensembl Protein ENSP00000359111
InnateDB Gene IDBG-89977 (IDH3G)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 15 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 15 [view]
Protein-Protein 15 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000287 magnesium ion binding
GO:0004449 isocitrate dehydrogenase (NAD+) activity
GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
GO:0051287 NAD binding
Biological Process
GO:0006099 tricarboxylic acid cycle
GO:0055114 oxidation-reduction process
Cellular Component
GO:0005730 nucleolus
GO:0005739 mitochondrion
Protein Structure and Domains
PDB ID
InterPro IPR004434 Isocitrate dehydrogenase NAD-dependent
IPR024084 Isopropylmalate dehydrogenase-like domain
PFAM PF00180
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q2Q9S4
UniProt Splice Variant
Entrez Gene 3421
UniGene Hs.410197
RefSeq
HUGO HGNC:5386
OMIM 300089
CCDS
HPRD 02100
IMGT
EMBL DQ173592 DQ173593 DQ173594 DQ173595 DQ173597 DQ173598 DQ173599 DQ173600 DQ173601 DQ173602 DQ173603 DQ173604 DQ173605 DQ173606 DQ173607 DQ173608 DQ173609 DQ173610 DQ173611 DQ173612 DQ173613 DQ173614 DQ173615 DQ173616 DQ173617 DQ173618 DQ173619 DQ173620 DQ173621 DQ173622 DQ173626 DQ173627 DQ173628 DQ173629 DQ173632 DQ173639 DQ173640 U52111
GenPept ABC25729 ABC25734 ABC25739 ABC25744 ABC25754 ABC25758 ABC25763 ABC25768 ABC25773 ABC25778 ABC25783 ABC25788 ABC25793 ABC25798 ABC25803 ABC25808 ABC25813 ABC25818 ABC25823 ABC25828 ABC25833 ABC25838 ABC25843 ABC25848 ABC25853 ABC25858 ABC25863 ABC25868 ABC25873 ABC25878 ABC25898 ABC25903 ABC25908 ABC25913 ABC25928 ABC25963 ABC25968

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca