Version 5.4
Homo sapiens Protein: TMEM204
Summary
InnateDB Protein IDBP-9079.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TMEM204
Protein Name transmembrane protein 204
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000253934
InnateDB Gene IDBG-9077 (TMEM204)
Protein Structure
UniProt Annotation
Function Can influence paracellular permeability. Appears to be involved in cell-cell interactions through adherens.
Subcellular Localization Cell junction, adherens junction {ECO:0000269PubMed:15206924}. Cell membrane {ECO:0000269PubMed:15206924}; Multi-pass membrane protein {ECO:0000269PubMed:15206924}. Note=Colocalizes with the beta- catenin adherins.
Disease Associations
Tissue Specificity Highly expressed in lung, heart, kidney and placenta. Lower expression in thymus, spleen, liver, testis and ovary. Expressed in endothelial and restricted epithelial cell populations. {ECO:0000269PubMed:15206924}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0006950 response to stress
Cellular Component
GO:0005886 plasma membrane
GO:0005912 adherens junction
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9BSN7
PhosphoSite PhosphoSite-Q9BSN7
TrEMBL
UniProt Splice Variant
Entrez Gene 79652
UniGene Hs.666512
RefSeq NP_001243470
HUGO HGNC:14158
OMIM 611002
CCDS CCDS42098
HPRD
IMGT
EMBL AE006467 AK024551 AY358178 AY676494 BC004932 BC105785 CH471112
GenPept AAH04932 AAI05786 AAK61286 AAQ88545 AAT78423 BAB14926 EAW85645 EAW85646

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca